Ligand- and Structure-Based Drug Design Strategies and PPARδ/α Selectivity
نویسندگان
چکیده
منابع مشابه
Drug Design: Structure- and Ligand-Based Approaches
Structure-based drug design (SBDD) and ligand-based drug design (LBDD) are active areas of research in both the academic and commercial realms. This book provides a current snapshot of the field of computer-aided drug design and associated experimental approaches. Topics covered include x-ray crystallography, nuclear magnetic resonance, fragment-based drug design, free-energy methods, docking a...
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Pharmaceutical research has successfully incorporated a wealth of molecular modeling methods, within a variety of drug discovery programs, to study complex biological and chemical systems. The integration of computational and experimental strategies has been of great value in the identification and development of novel promising compounds. Broadly used in modern drug design, molecular docking m...
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ژورنال
عنوان ژورنال: Chemical Biology & Drug Design
سال: 2012
ISSN: 1747-0277
DOI: 10.1111/j.1747-0285.2012.01424.x